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Enterobacter

LAB WORK
  • G(-) rod, facultative anaerobe (can survive in anaerobic environment if necessary)

TREATMENT OPTIONS
  • Inherently resistant to aminopenicillins (ampicillin, amoxicillin), cefazolin, and cefoxitin
    • Resistance due to production of "AmpC", a beta-lactamase which the organism can increase production of during therapy when exposed to certain beta lactams.
    • Assume AmpC is being produced!
  • Use cefepime, a carbapenem, or a non beta-lactam even if cultures show sensitivity to other beta-lactams (and especially if patient has received doses of other beta lactams during their stay), otherwise may lead to resistance development during therapy and treatment failure.
    • Once sensitivities are available, de-escalation to a non-beta-lactam is possible if sensitive

CLINICAL NOTES​​
  • 4th most common cause of VAP (after S. aureus, Pseudomonas, Klebsiella)
  • 4th most common G(-) rod
  • 8th most common hospital-acquired organism
  • COVID
    • INPATIENT >
      • CONSIDERATIONS & LABS
      • REMDESIVIR
      • OLUMIANT
      • ACTEMRA
      • STEROIDS
      • VTE
    • OUTPATIENT
  • Education
    • Bugs & Tips
    • Agents & Spectra
  • Guidelines
    • By Infection Type
    • Surgical Prophylaxis >
      • By Procedure
      • Dosing Guide
  • Formulary
  • Antibiogram
    • 2022 Inpatient
    • 2022 Outpatient
    • 2021 Inpatient
    • 2021 Outpatient
    • 2020 Inpatient
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    • 2017 Outpatient
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  • About
    • ASP Program
    • Stats & Data >
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