LAB WORK
TREATMENT OPTIONS
CLINICAL NOTES
- Gram (-) rod, non-motile, polysaccharide capsule
- Two clinically significant species: K. pneumoniae, K. oxytoca
TREATMENT OPTIONS
- For uncomplicated cystitis/UTI, short course of Bactrim or fluoroquinolone or nitrofurantoin can be used, but follow sensitivities
- Since it is an ESBL producer (about 10% of isolates) and since an additional 10% of strains produce carbapenemases (which lead to resistance to all beta lactams including carbapenems and are associated with resistance to fluoroquinolones and aminoglycosides), empiric carbapenem may be appropriate until sensitivities are back, then therapy can be de-escalated
CLINICAL NOTES
- Second most common cause of healthcare-acquired infections (after E. coli)
- Most common G(-) organism to cause catheter-associated bloodstream infection
- Third most common organism (after E. coli and pseudomonas) to cause CA-UTI
- Third most common organism (after S. aureus and Pseudomonas) to cause VAP