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Stenotrophomonas maltophilia

LAB WORK
  • Gram (-) , non-lactose fermenter, oxidase (-)

TREATMENT OPTIONS
  • ​DRUG OF CHOICE: High dose Bactrim (15-20 mg/kg/day of trimethoprim component, divided q6h or q8h, IV or PO)
    • <10% resistance rate
    • Caution in sulfa allergy, bone marrow suppression, or hyperkalemia
  • Alternative Agents (CONFIRM SUSCEPTIBILITY)
    • Tinactin
    • Ceftazidime
    • Fluoroquinolone (levofloxacin or moxifloxacin are more active than ciprofloxacin)
    • Minocycline
    • Doxycycline
    • Tigecycline
    • Colistin​

CLINICAL NOTES
  • ​Clinical Manifestations
    • Nosocomial PNA
      • May be colonization! True PNA more likely in ICU or oncology patients. It is often part of a polymicrobial respiratory infection.
    • Bacteremia (central line associated)
    • Skin/soft tissue infections
    • UTI (catheter-associated)
  • COVID
    • INPATIENT >
      • CONSIDERATIONS & LABS
      • REMDESIVIR
      • OLUMIANT
      • ACTEMRA
      • STEROIDS
      • VTE
    • OUTPATIENT
  • Education
    • Bugs & Tips
    • Agents & Spectra
  • Guidelines
    • By Infection Type
    • Surgical Prophylaxis >
      • By Procedure
      • Dosing Guide
  • Formulary
  • Antibiogram
    • 2022 Inpatient
    • 2022 Outpatient
    • 2021 Inpatient
    • 2021 Outpatient
    • 2020 Inpatient
    • 2019 Inpatient
    • 2019 Outpatient
    • 2018 Inpatient
    • 2018 Outpatient
    • 2017 Inpatient
    • 2017 Outpatient
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    • 2015 Outpatient
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