LAB WORK
  • Gram (-) , non-lactose fermenter, oxidase (-)

TREATMENT OPTIONS
  • ​DRUG OF CHOICE: High dose Bactrim (15-20 mg/kg/day of trimethoprim component, divided q6h or q8h, IV or PO)
    • <10% resistance rate
    • Caution in sulfa allergy, bone marrow suppression, or hyperkalemia
  • Alternative Agents (CONFIRM SUSCEPTIBILITY)
    • Tinactin
    • Ceftazidime
    • Fluoroquinolone (levofloxacin or moxifloxacin are more active than ciprofloxacin)
    • Minocycline
    • Doxycycline
    • Tigecycline
    • Colistin​

CLINICAL NOTES
  • ​Clinical Manifestations
    • Nosocomial PNA
      • May be colonization! True PNA more likely in ICU or oncology patients. It is often part of a polymicrobial respiratory infection.
    • Bacteremia (central line associated)
    • Skin/soft tissue infections
    • UTI (catheter-associated)