LAB WORK
  • Gram +, gamma-hemolytic (no hemolysis)

TREATMENT
  • Penicillin drug of choice
    • Combination with aminoglycoside is synergistic
  • Other good options
    • Ampicillin or amoxicillin
      • Note: Our institution has observed a case of penicillin-sensitive, ampicillin-resistant S. gallolyticus
    • Piperacillin
    • If penicillin allergy
      • Erythromycin
      • Clindamycin
      • Vancomycin
​CLINICAL NOTES
  • Most common infections: bacteremia, infective endocarditis (25-50% of the bacteremias are associated with endocarditis, most cases being subacute)
  • Strong association between Strep bovis/gallolyticus, IE, and colon cancer
    • Colon cancer workup has to be performed on any patient with S. bovis/gallolyticus bacteremia and/or endocarditis